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In double-blinded, vehicle-controlled clinical studies, many patients in the vehicle group achieved desired palliative effects on tretinoin fine wrinkling of facial skin with the use of comprehensive skin care and sunlight avoidance programs including tretinoin sunscreens, protective clothing, and non-prescription emollient creams. Renova (tretinoin cream).02 does NOT eliminate wrinkles, repair SUN-damaged skin, tretinoin reverse photoaging, or restore more youthful or younger skin. Renova (tretinoin cream).02 should be used tretinoin under tretinoin medical tretinoin supervision as an adjunct to tretinoin a comprehensive skin care and sunlight avoidance program that includes the use of effective sunscreens (minimum SPF of 15) and protective clothing. 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